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Updated: Jul 7, 2026

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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Advances in approaches to the cranial base: minimizing morbidity
Michael R Shohet1, Kurt Laedrach, Raphael Guzman
1Department of Otolaryngology-Head and Neck Surgery, Mount Sinai School of Medicine, New York, New York 10029, USA.
Facial Plastic Surgery : FPS
|February 21, 2008
Summary
Minimally invasive cranial base surgery advances allow complete tumor resection and watertight reconstruction with reduced morbidity. Endoscopic approaches show promise for benign conditions, but long-term cancer data is pending.
Area of Science:
- Neurosurgery
- Skull Base Surgery
- Minimally Invasive Techniques
Background:
- Cranial base surgery has advanced significantly, focusing on complete tumor resection and reconstruction.
- The subcranial/subfrontal approach, initially for trauma, is now used for tumors and anomalies.
- Endoscopic techniques offer practical benefits for various skull base disorders.
Purpose of the Study:
- To review recent innovations in cranial base surgery.
- To highlight the evolution and application of surgical approaches.
- To assess the efficacy and limitations of current techniques, particularly endoscopic methods.
Main Methods:
- Review of historical and recent surgical approaches for cranial base pathologies.
- Discussion of subcranial/subfrontal and endoscopic techniques.
- Evaluation of outcomes including resection completeness, reconstruction, morbidity, and recovery.
Main Results:
- Innovative techniques enable complete resection and watertight reconstruction with minimal incisions.
- Endoscopic approaches demonstrate practical utility and promising efficacy for benign, infectious, and inflammatory skull base disorders.
- Advantages include minimal recovery time, functional preservation, and aesthetic benefits.
Conclusions:
- Modern cranial base surgery prioritizes maximal resection and reconstruction with minimal patient impact.
- Endoscopic surgery is effective for non-malignant conditions, offering significant patient benefits.
- Further long-term data is required to establish the efficacy of endoscopic approaches for malignancies.
