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Updated: Jul 7, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
Published on: January 26, 2016
Applications of the combination of microwave and parallel synthesis in medicinal chemistry
Jesús Alcázar1, Gaston Dielsb, Bruno Schoentjes
1Johnson & Johnson Pharmaceutical Research and Development, Division of Janssen-Cilag, S.A. Jarama 75, Toledo, Spain. jalcazar@prdes.jnj.com
Abstract:
The blending of microwave heating and parallel chemistry is a logical consequence of the significant rate enhancement and higher product yield afforded by microwave technology and the increase in productivity afforded by combinatorial chemistry. For this reason, this combination has become increasingly popular in the organic chemistry community. The current review highlights the application of this approach as a way to increase the rate of analogue synthesis in medicinal chemistry.
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