Related Experiment Video
Updated: Jul 7, 2026

Mapping Dysfunctional Protein-Protein Interactions in Disease
Published on: October 24, 2025
DPA: a deterministic approach to the MAP problem
Abstract:
Deterministic pseudo-annealing (DPA) is a new deterministic optimization method for finding the maximum a posteriori (MAP) labeling in a Markov random field, in which the probability of a tentative labeling is extended to a merit function on continuous labelings. This function is made convex by changing its definition domain. This unambiguous maximization problem is solved, and the solution is followed down to the original domain, yielding a good, if suboptimal, solution to the original labeling assignment problem. The performance of DPA is analyzed on randomly weighted graphs.
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