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Serum alpha-1-antitriypsin levels in patients with pseudoexfolative syndrome
Tongabay Cumurcu1, Huseyin Ozyurt, Helin Deniz Demir
1Department of Ophthalmology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. tongabay@superonline.com
Purpose:
To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX.
Material And Methods:
Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry.
Results:
The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001).
Conclusion:
Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
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