Related Experiment Video

Updated: Jul 7, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

The importance of left ventricular function for long-term outcome after primary percutaneous coronary intervention

Pieter A van der Vleuten1, Saman Rasoul, Willem Huurnink

  • 1Thoraxcentre, Department of Cardiology, University Medical Centre Groningen, The Netherlands. p.a.van.der.vleuten@thorax.umcg.nl

BMC Cardiovascular Disorders
|February 26, 2008
PubMed

Insights

Left ventricular ejection fraction (LVEF), measured by planar radionuclide ventriculography (PRV), is a strong predictor of long-term mortality after ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI). This finding highlights LVEF

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Medical Imaging

Background:

  • ST-elevation myocardial infarction (STEMI) requires timely intervention.
  • Primary percutaneous coronary intervention (PPCI) is a standard treatment for STEMI.
  • Assessing left ventricular ejection fraction (LVEF) is crucial for prognosis.

Purpose of the Study:

  • To evaluate the long-term prognostic significance of LVEF.
  • To determine the predictive value of LVEF assessed by planar radionuclide ventriculography (PRV).
  • To analyze LVEF in patients with STEMI treated with PPCI.

Main Methods:

  • 925 patients with STEMI treated with PPCI underwent PRV.
  • LVEF was assessed using 99mTc-pertechnetate.
  • Average follow-up duration was 2.5 years.

Main Results:

  • Mean LVEF was 45.7 ± 12.2%.
  • Univariate predictors of mortality included Killip class, multivessel disease, prior cardiovascular events, peak creatine kinase-MB, age, and LVEF.
  • Age and LVEF independently predicted 1- and 3-year mortality in Cox regression analysis.

Conclusions:

  • LVEF measured by PRV is a potent independent predictor of long-term mortality.
  • This assessment is vital for risk stratification in STEMI patients post-PPCI.
Abstract

More Related Videos

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice08:21

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...