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Periosteal osteosarcoma in the hand of a pediatric patient: a case report

Traske M Muir1, Thomas P Lehman, William H Meyer

  • 1Department of Orthopedic Surgery & Rehabilitation, University of Oklahoma, Oklahoma City, OK 73117-1026, USA.

The Journal of Hand Surgery
|February 26, 2008
PubMed

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Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...