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Suppression of the cr-1 mutation in Neurospora crassa
S Kore-eda1, T Murayama, I Uno
1Institute of Applied Microbiology, University of Tokyo.
Idengaku Zasshi
|February 1, 1991
Abstract:
We have cloned a DNA fragment, which hybridized with the adenylate cyclase gene (CYR1) of Saccharomyces cerevisiae, from genomic DNA libraries of Neurospora crassa. The cr-1 mutation was able to be suppressed by introducing this DNA fragment on a cosmid vector, judging from recovery of the adenylate cyclase activity and the abnormal morphology.