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Related Concept Videos

Structure of Lipids03:38

Structure of Lipids

Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic birds and...
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Lipids: Dietary Sources and Requirements01:18

Lipids: Dietary Sources and Requirements

Lipids are an essential component of a balanced human diet. Triglycerides, which make up the majority of dietary lipids, are found in both saturated fats—commonly present in meat, dairy products, and certain tropical plants like coconut, and hydrogenated oils such as margarine and baking shortenings (trans fats)—and unsaturated fats, which are abundant in seeds, nuts, olive oil, and most vegetable oils. The main sources of cholesterol include egg yolks, various meats and organ meats, shellfish,...
Compounds Essential to Human Function01:25

Compounds Essential to Human Function

The human body is composed of cells that are fundamentally made up of several different molecules. These molecules are essential to carry out all physiological processes in the body and are broadly classified into organic and inorganic based on their chemical structures.
Inorganic Compounds Essential to Human Functioning
Inorganic compounds essential to human functioning include water, salts, acids, and bases. These compounds are inorganic, i.e., they do not have a carbon-hydrogen bond. Water...
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

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Updated: Jul 7, 2026

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
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Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans

Published on: December 9, 2022

N-3 long-chain polyunsaturated fatty acids for optimal function during brain development and ageing.

Alan D Dangour1, Ricardo Uauy

  • 1Nutrition and Public Health Intervention Research Unit, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Asia Pacific Journal of Clinical Nutrition
|May 28, 2008
PubMed
Summary

n-3 long chain polyunsaturated fatty acids (n-3 LCPs) support infant visual and cognitive development. Emerging evidence suggests n-3 LCPs may also benefit cognitive health in older adults, with ongoing trials investigating their role in preventing age-related cognitive decline.

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Last Updated: Jul 7, 2026

Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans
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Lipid Supplementation for Longevity and Gene Transcriptional Analysis in Caenorhabditis elegans

Published on: December 9, 2022

Dietary Supplementation of Polyunsaturated Fatty Acids in Caenorhabditis elegans
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Dietary Supplementation of Polyunsaturated Fatty Acids in Caenorhabditis elegans

Published on: November 29, 2013

Lipidomics and Transcriptomics in Neurological Diseases
09:58

Lipidomics and Transcriptomics in Neurological Diseases

Published on: March 18, 2022

Area of Science:

  • Nutrition Science
  • Neuroscience
  • Ophthalmology

Background:

  • n-3 long chain polyunsaturated fatty acids (n-3 LCPs) are crucial for infant development.
  • Early n-3 LCP supplementation in infants shows benefits for visual acuity and cognitive function.
  • The role of n-3 LCPs in older adults' cognitive health is an emerging area of research.

Purpose of the Study:

  • To review the evidence for n-3 LCPs in visual and cognitive development across the lifespan.
  • To highlight the potential of n-3 LCPs in maintaining cognitive function in older age.
  • To introduce an ongoing randomized controlled trial assessing n-3 LCPs for retinal function and cognitive decline prevention in older adults.

Main Methods:

  • Literature review of studies on n-3 LCPs in infant, child, and adult populations.
  • Analysis of cross-sectional and prospective cohort studies on n-3 LCPs and cognitive function in older adults.
  • Description of a current randomized controlled trial in adults aged 70-79 years.

Main Results:

  • n-3 LCPs are associated with enhanced visual acuity and cognitive abilities in infants and young children.
  • Studies suggest a link between higher n-3 LCP intake/blood levels and reduced risk of cognitive impairment and dementia in older adults.
  • Evidence for n-3 LCPs enhancing learning or behavior in school-aged children is currently limited.

Conclusions:

  • Early n-3 LCP provision is vital for optimal visual and cognitive development in infants.
  • n-3 LCPs show promise for preserving cognitive health and retinal function in aging populations.
  • Further research, including ongoing trials, is needed to confirm the benefits of n-3 LCP supplementation in older adults.