Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intermediate Term Results of a Novel Minimally Invasive Keratoprosthesis.

Ophthalmology science·2026

Same author

Genetic phenotypic characteristics and inheritance patterns of patients with achromatopsia at a large academic institution and a review of the literature and gene therapies.

Molecular vision·2026

Same author

Corneal Endothelial Keratoplasty After Glaucoma Treatment: An American Academy of Ophthalmology IRIS® Registry Analysis.

Ophthalmology. Glaucoma·2026

Same author

Complement Factor H (Y402H) polymorphism for age-related macular degeneration alters retinal lipids.

bioRxiv : the preprint server for biology·2026

Same author

Surgical Techniques and Indications for Intraocular Lens Explantation: A Narrative Review.

Clinical ophthalmology (Auckland, N.Z.)·2025

Same author

Delphi-Based Global Consensus on Fuchs Endothelial Corneal Dystrophy. An Endothelial Keratoplasty Learners Group Initiative.

American journal of ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Optic neuropathy after epi-LASIK.

Sandra R Montezuma¹, Simmons Lessell, Roberto Pineda

¹Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Mass 02114, USA. Sandra_Montezuma@meei.harvard.edu

Journal of Refractive Surgery (Thorofare, N.J. : 1995)

|February 27, 2008

Summary

This summary is machine-generated.

Epi-LASIK surgery can cause optic neuropathy, a serious vision complication. This case suggests barotrauma from suction rings may be a contributing factor, requiring careful monitoring and management.

More Related Videos

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

Related Experiment Videos

Last Updated: Jul 7, 2026

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients

Published on: August 2, 2024

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

Area of Science:

Ophthalmology
Surgical Complications

Background:

Epi-LASIK (epithelial laser-assisted in situ keratomileusis) is a refractive surgical procedure.
Optic neuropathy is a condition affecting the optic nerve, potentially leading to vision loss.

Observation:

A 24-year-old male patient developed optic neuropathy following epi-LASIK surgery.
The condition was potentially linked to barotrauma caused by the suction ring used during the procedure.
The patient was also diagnosed with steroid-induced ocular hypertension.

Findings:

Treatment involved discontinuing prednisolone eye drops and initiating timolol.
The patient's symptoms, including pain, showed improvement within two weeks of treatment.
Optic neuropathy following epi-LASIK is a vision-threatening complication.

Implications:

Barotrauma from increased intraocular pressure during epi-LASIK may be a significant factor in developing optic neuropathy.
This case highlights the importance of recognizing and managing this potential complication.
Further research may be needed to elucidate the exact mechanisms and preventative strategies.