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Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Histopathologic diagnosis of lymph node biopsies
M Tiwari1, G Aryal, R Shrestha
1Department of Pathology, Nepal Medical College, Kathmandu, Nepal.
Nepal Medical College Journal : NMCJ
|February 27, 2008
Summary
Tuberculosis is the primary cause of lymphadenopathy in Nepal, affecting more females than males. This finding highlights the need for targeted public health interventions for this common condition.
Area of Science:
- Pathology
- Infectious Diseases
- Public Health
Background:
- Lymphadenopathy is a common clinical finding with diverse etiologies.
- Understanding the epidemiological profile of lymphadenopathy is crucial for effective healthcare planning in developing countries.
Purpose of the Study:
- To determine the etiological spectrum and demographic characteristics of lymphadenopathy in Nepal.
- To identify the most frequent lymph node group affected by lymphadenopathy.
Main Methods:
- Retrospective analysis of 55 lymph node biopsies received at Nepal Medical College from January 2004 to December 2005.
- Data collected included patient demographics and histopathological findings.
Main Results:
- Tuberculosis was the leading cause of lymphadenopathy, accounting for the majority of cases.
- Cervical lymph nodes were the most commonly involved group.
- Females constituted 56.0% of cases, with a M:F ratio of 1:1.29.
- Metastatic deposits were identified in only six cases.
Conclusions:
- Tuberculosis remains the predominant cause of lymphadenopathy in Nepal, similar to trends in other developing nations.
- Cervical lymph node tuberculosis is a significant public health concern in the region.
- Further research into diagnostic and treatment strategies for tuberculous lymphadenopathy is warranted.
