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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jul 7, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Canine and feline uveitis.

Wendy M Townsend1

  • 1Department of Small Animal Clinical Sciences, D208 Veterinary Medical Center, Michigan State University, East Lansing, MI 48824-1314, USA. townsend@vcm.msu.edu

The Veterinary Clinics of North America. Small Animal Practice
|February 27, 2008
PubMed
Summary

Uveitis is eye inflammation causing vision loss and pain. Identifying the cause is key, though many cases are idiopathic, requiring treatment to preserve sight.

Area of Science:

  • Ophthalmology
  • Immunology
  • Pathology

Background:

  • Uveitis involves inflammation of the eye's vascular layer.
  • This inflammation disrupts the blood-aqueous and blood-retinal barriers.
  • Numerous infectious and non-infectious agents can trigger uveitis.

Purpose of the Study:

  • To summarize the clinical presentation and management principles of uveitis.
  • To highlight the importance of diagnosing the underlying cause of uveitis.
  • To outline therapeutic goals for uveitis patients.

Main Methods:

  • Review of clinical signs associated with uveitis.
  • Discussion of potential etiologic agents (infectious and non-infectious).
  • Emphasis on diagnostic evaluation and idiopathic cases.

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Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Jul 7, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Main Results:

  • Clinical signs stem from inflammation and barrier breakdown.
  • Idiopathic cases are common despite diagnostic efforts.
  • Therapeutic success depends on addressing inflammation and preserving vision.

Conclusions:

  • Uveitis management focuses on vision preservation, pain reduction, and inflammation control.
  • Comprehensive diagnostics are recommended but may not yield an etiology.
  • Understanding the pathophysiology is crucial for effective uveitis treatment.