Related Experiment Video
Updated: Nov 16, 2025

Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
Published on: September 17, 2014
Double drape tectonic patch with cyanoacrylate glue for surgical repair of corneal defects: 8 cases
Elena N Rodriguez1, Wendy M Townsend1, Jean Stiles1
1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA.
Objective:
To describe the use of a double drape tectonic patch with cyanoacrylate glue technique for the treatment of deep or penetrating corneal defects in cats and dogs.
Animals Studied:
Eight client-owned animals of which five were cats and three were dogs.
Procedure:
Eight cases: Four with descemetoceles, three with corneal perforations, and one with a deep stromal ulcer were treated with a double layer of plastic drape material adhered to the cornea with a cyanoacrylate (2-octyl or 2-octyl, N-butyl)-based tissue adhesive. The patch was then covered with a third eyelid flap.
Results:
Seven of the eight eyes healed uneventfully with a median time to healing time of 20 days (range 14-28 days). After healing, the glue patch had loosened and was removed. One eye of one cat developed bacterial keratitis with an iris prolapse adjacent to the patch and was subsequently enucleated. Only two of the eight eyes had increased corneal neovascularization.
Conclusion:
Treatment of deep or penetrating corneal defects with a double drape tectonic patch and cyanoacrylate glue is a viable option which may be a faster and less expensive alternative to other globe sparing surgical options.

