Related Experiment Video
Updated: Sep 12, 2026
Optimizing Tear Collection in Mice for mRNA and Protein Analysis
Published on: July 19, 2024
Effect of Order of Testing on Intraocular Pressure and Tear Production Measurement in Dogs
Kate Rowatt Keenen1, Daniel Keenen2, Elizabeth Adkins1
1Hope Advanced Ophthalmology, Vienna, Virginia, USA.
Objective:
To determine if the order of performing Schirmer tear test -1 (STT-1) and intraocular pressure (IOP) using a rebound tonometer influences the diagnostic values in a general population of dogs.
Animals Studied:
122 eyes from 61 dogs of a variety of signalments and presentations.
Procedures:
Dogs were randomly assigned into IOP first (Group A) and STT-1 first (Group B) groups. Each group had an STT-1 test, IOP measured by rebound tonometry, fluorescein staining, and a complete ocular examination.
Results:
No significant differences were found between Group A and Group B for either tear production (p = 0.62) or IOP (p = 0.27). There were no significant differences with gender for both groups, and no significant difference was found between left and right eyes for IOP when left eyes were measured first.
Conclusions:
The order of performing STT-1 and rebound tonometry has no significant effect on tear production or IOP for a general population of dogs. The order of testing is unlikely to have a clinically significant effect.
More Related Videos
08:04A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
Published on: January 24, 2020
10:10Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
Published on: February 15, 2022