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Updated: Jul 7, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
The "Golden Age" of prostate brachytherapy: a cautionary tale
1University of Massachusetts Medical School, Worcester, MA 01605, USA. aronowij@ummhc.org
Purpose:
To investigate the earliest attempts to use man-made isotopes for prostate brachytherapy.
Methods And Materials:
Two radiogold brachytherapy programs were analyzed, using literature review and interviews of participants.
Results:
Although (198)Au has been discredited as a source for permanent prostate brachytherapy, the major flaw in the reviewed programs was the misapplication of the isotope.
Conclusions:
Safe and effective implant programs are grounded in the sound application of brachytherapy principles. New brachytherapy procedures should arise from the collaboration of radiation oncologists, surgeons, physicists, radiobiologists, and radiation safety specialists.

