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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Related Experiment Video

Updated: Feb 28, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

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New developments in optical coherence tomography for glaucoma.

Robert Chang1, Donald L Budenz

  • 1Bascom Palmer Eye Institute, Miami, Florida 33136, USA. rchang3@med.miami.edu

Current Opinion in Ophthalmology
|February 28, 2008
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) is a reliable tool for imaging the retinal nerve fiber layer in glaucoma. Understanding OCT

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Structural imaging is crucial for diagnosing and monitoring glaucoma progression.
  • Optical coherence tomography (OCT) is a rapidly evolving imaging technology.
  • Keeping up with advancements in OCT for glaucoma can be challenging.

Purpose of the Study:

  • To review recent literature on optical coherence tomography (OCT) for glaucoma.
  • To provide an update on the latest developments in OCT technology for glaucoma assessment.

Main Methods:

  • Review of recent scientific papers on optical coherence tomography in glaucoma.
  • Analysis of current strengths and limitations of OCT technology.

Main Results:

  • Retinal nerve fiber layer imaging using OCT is reliable.
  • Factors such as age, ethnicity, axial length, and optic disc size influence normative ranges.
  • Scan quality can be impacted by patient movement, media opacities, myopia, and disease severity.
  • Sensitivity and specificity vary across studies, but OCT aids in understanding the structure-function relationship in glaucoma.

Conclusions:

  • Next-generation OCT technology is emerging.
  • Understanding current OCT capabilities and limitations is essential for effective clinical application.
  • This review helps clinicians assess the utility of OCT in practice.