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Updated: Jul 7, 2026

Corneal and Limbal Alkali Injury Induction Using a Punch-Trephine Technique in a Mouse Model
Published on: August 4, 2023
Corneal epithelial inclusion cyst in a Llama
Chris G Pirie1, Stefano Pizzirani, Nicola M Parry
1Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA. stefano.pizzirani@tufts.edu
Abstract:
A 13-year-old, female Llama presented for evaluation of a limbal based corneal mass involving the OD of 4 months duration. The mass was excised en bloc by a nonpenetrating keratectomy, followed by placement of a conjunctival advancement flap covering the keratectomy site. The mass was submitted for histological evaluation. Histopathology identified the mass to be a corneal epithelial inclusion cyst filled with necrotic squamous and neutrophilic debris. Surgical excision was complete and considered curative with no signs of recurrence 3 months postoperatively. There was no known prior ocular trauma; however, a previously performed corneal biopsy for evaluation of recurrent epithelial erosions may have been an initiating cause.
