Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Mechanical Ventilation I: Indication and Settings

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Assessment of Ventilation I: Respiratory Rate

Assessment of Ventilation I: Respiratory Rate

Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:

Ventilatory Modes

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

Respiratory Volumes and Capacities

Respiratory Volumes and Capacities

The respiratory system is responsible for the intake of oxygen and the expulsion of carbon dioxide from the body. Respiratory volumes describe the volume of air in the lungs at different phases of the respiratory cycle. Tidal volume is the air breathed in and out during normal, quiet breathing. Inspiratory reserve volume is the air that can be forcefully inspired beyond the tidal volume. In contrast, expiratory reserve volume refers to the air that can be expelled from the lungs after a normal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Pertussistoxin as well as Staphylococcal superantigen induce glycolysis as energy source during T cell activation in an adenoid organoid model.

Clinical science (London, England : 1979)·2026

Same author

[Microvascular Reconstruction of the Laryngotracheal Junction].

Zentralblatt fur Chirurgie·2026

Same author

Submental artery island flap for reconstruction of lateral oropharyngeal carcinoma in patients with severe anesthesiological risk factors: Functional and oncologic outcomes.

Molecular and clinical oncology·2026

Same author

Spinless and Spinful Charge Excitations in Moiré Fractional Chern Insulators.

Physical review letters·2026

Same author

Assessing Ecological Connectivity for <i>Loxodonta africana</i> Across Transfrontier Conservation Areas in Southern Mozambique.

Ecology and evolution·2026

Same author

[Fever in children and adolescents in otorhinolaryngology : Practical overview based on the German S3 guideline].

HNO·2026

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

A ventilator requirement index.

John R Bach¹, Miguel Goncalves, Michal Eisenberg

¹Department of Physical Medicine and Rehabilitation, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA.

American Journal of Physical Medicine & Rehabilitation

|February 28, 2008

Summary

This summary is machine-generated.

Vital capacity (VC) and the ventilator requirement index (VRI) effectively predict the need for mechanical ventilation in patients with neuromuscular/chest wall diseases. These measures help justify ventilator prescription and ensure optimal patient benefit.

Related Experiment Videos

Last Updated: Jul 7, 2026

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

Published on: September 6, 2024

Area of Science:

Respiratory Medicine
Pulmonary Physiology
Medical Device Engineering

Background:

Neuromuscular/chest wall diseases (NMD) significantly impair respiratory function.
Objective assessment is crucial for appropriate ventilator prescription in NMD patients.
Current methods for determining ventilator need in NMD may lack precision.

Purpose of the Study:

To evaluate the efficacy of vital capacity (VC) and a novel ventilator requirement index (VRI) in justifying ventilator prescription for NMD patients.
To determine if VC and VRI can accurately predict the level of ventilator support required.

Main Methods:

A prospective observational study involving 319 NMD patients, with 187 on ventilators.
Patients were categorized into four groups based on symptoms and ventilator use duration (0-20+ hours/day).
The VRI was calculated using the formula: 60 x Ti/(Ttot)^2 x (Vt/VC) x RR.

Main Results:

Significant differences in VC and VRI were observed across all patient groups (P < 0.001).
Both VC and VRI independently predicted group membership.
Meeting VC or VRI criteria identified the largest number of patients who benefited from ventilator use.

Conclusions:

Vital capacity (VC) and the ventilator requirement index (VRI) are effective tools for justifying ventilator prescription in NMD.
The combination of VC and VRI offers the highest sensitivity for identifying patients who will benefit from ventilation.
These indices can support decisions regarding the prescription of one or two ventilators.