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Updated: Jul 7, 2026

Dissection and Flat-mounting of the Threespine Stickleback Branchial Skeleton
Published on: May 7, 2016
An approach to the core skeleton of lancifodilactone F
1Department of Biochemistry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, USA.
Abstract:
Two cycloaddition reactions were utilized for the construction of the 5,6,7-tricyclic skeleton of lancifodilactone F and buxapentalactone. A [2+2] ketene cycloaddition reaction was first used to set their adjacent all-carbon quaternary centers at the 5,6-ring junction. An arene-olefin meta-photocycloaddition reaction was then used to install the 6- and 7-membered rings concurrently.
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