DBMLoc: a Database of proteins with multiple subcellular localizations

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Updated: Jul 7, 2026

Enriching Subcellular Proteins in Leptospira Using a Triton X-114-Based Fractionation Approach
04:25

Enriching Subcellular Proteins in Leptospira Using a Triton X-114-Based Fractionation Approach

Published on: August 8, 2025

Song Zhang1, Xuefeng Xia, Jincheng Shen

  • 1MOE Key Laboratory of Bioinformatics, State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China. zhangsong04@mails.tsinghua.edu.cn

BMC Bioinformatics
|February 29, 2008
PubMed
Abstract

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Protein Networks

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Ligand Binding and Linkage

Allosteric proteins have more than one ligand binding site; the binding of a ligand to any of these sites influences the binding of ligands to the other sites. When a protein is allosteric, its binding sites are called coupled or linked.  In the case of enzymes, the site that binds to the substrate is known as the active site and the other site is known as the regulatory site. When a ligand binds to the regulatory site, this leads to conformational changes in the protein that can influence the...
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Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

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