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Updated: Jul 7, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Effect of systemic corticosteroids on elective left-sided colorectal resection with colorectal anastomosis
Christophe Trésallet1, Benoit Royer, Gaëlle Godiris-Petit
1Department of General and Digestive Surgery, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie (Paris VI), 75651 Paris Cedex 13, France. christophe.tresallet@psl.aphp.fr
Background:
The impact of systemic steroid therapy on surgical outcome after elective left-sided colorectal resection with rectal anastomosis is not well known.
Methods:
We compared 606 consecutive patients including 53 patients who were on steroids and undergoing surgery between 1995 and 2005.
Results:
Postoperative mortality and anastomotic leakage rates were equivalent. The postoperative complications rate, especially infections, was higher in steroid-treated patients than in non-steroid-treated patients: 38% (20 of 53 patients) versus 25% (139 of 553 patients), respectively (P = .046). In the steroid group, univariate analysis revealed 3 significant risk factors for postoperative complications: blood transfusion, preoperative anticoagulation, and chronic respiratory failure. In a multivariate analysis, blood transfusion and chronic respiratory failure remained independent factors for postoperative complications.
Conclusion:
Patients on steroids have a higher incidence of postoperative complications after elective left-sided colorectal resection with rectal anastomosis.
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