Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Ethical Dilemmas I

Ethical Dilemmas I

Ethical dilemmas in nursing are of utmost importance, as they often arise from the tension between adhering to core ethical principles and the practical realities of healthcare delivery. These dilemmas require nurses to navigate complex situations where competing ethical considerations pull them in different directions.
Let us explore some examples to understand the potentially complex moral decisions nurses face.
Take the case of caring for minors, particularly in areas related to reproductive...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Nursing Ethical Principles II

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...

Relationship with Other Adult Family Members and Siblings

Relationship with Other Adult Family Members and Siblings

Other adult family members and siblings play a crucial role in shaping children’s social and emotional development. While parents or primary caregivers are often the central figures in early attachment and socialization, other adults in a child’s life, such as grandparents, aunts, and uncles, can significantly influence developmental outcomes. These influences depend on each adult’s personality and may help compensate when a primary caregiver is emotionally distant or inconsistent. For...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Invasive Pneumococcal Disease After Hematopoietic Cell Transplantation for Sickle Cell Disease.

Transplant infectious disease : an official journal of the Transplantation Society·2026

Same author

The 2026 report mandated by the U.S. congress to assess the NIH support for pediatric research - strategies to enhance NIH-funded pediatric research: Optimizing child health.

Journal of pediatric nursing·2026

Same author

Quality domains in home-based pediatric hospice and palliative care: adolescent and young adult perspectives.

BMC palliative care·2026

Same author

The Vulnerables' Opportunity to Inform Culturally Congruent Care Education (VOICCCE) for nursing practice in the care of LGBTQ+ youth.

Journal of pediatric nursing·2026

Same author

Natural History of Morquio A Syndrome.

Journal of inherited metabolic disease·2026

Same author

Pediatric home-based hospice and palliative care: a scoping review.

BMC palliative care·2026

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Published on: November 10, 2023

The ethical justification for minor sibling bone marrow donation: a case study.

Rebecca D Pentz¹, Ann E Haight, Robert B Noll

¹Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USA. rpentz@emory.edu

|February 29, 2008

Summary

This case study explores ethical justifications for minor bone marrow donation, particularly for mentally delayed children. It suggests familial duty can ethically permit donation even if direct donor benefit is uncertain.

More Related Videos

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Published on: May 26, 2021

Femoral Bone Marrow Aspiration in Live Mice

Femoral Bone Marrow Aspiration in Live Mice

Published on: July 5, 2014

Related Experiment Videos

Last Updated: Jul 7, 2026

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Simplified Intrafemoral Injections Using Live Mice Allow for Continuous Bone Marrow Analysis

Published on: November 10, 2023

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Published on: May 26, 2021

Femoral Bone Marrow Aspiration in Live Mice

Femoral Bone Marrow Aspiration in Live Mice

Published on: July 5, 2014

Area of Science:

Medical Ethics
Pediatric Oncology
Hematology

Background:

Minor sibling bone marrow donation is typically justified by anticipated donor benefit.
Limited data exists on risks and benefits for pediatric donors.

Observation:

A case study involving a mentally delayed minor donating bone marrow for his sister is presented.
The transplant's success is not guaranteed, raising questions about direct donor benefit.

Findings:

The study argues that direct donor benefit is not always assured in minor bone marrow donation.
An alternative ethical justification based on familial duty is proposed.

Implications:

Increased support for minor bone marrow donors, especially those with cognitive impairments, is recommended.
Familial duty, considering relationship dynamics and risk-benefit analysis, offers an ethical basis for donation.