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Updated: Jul 7, 2026

Monitoring Tumor Metastases and Osteolytic Lesions with Bioluminescence and Micro CT Imaging
Published on: April 14, 2011
Two-dimensional imaging of dense tissue-simulating turbid media by use of sonoluminescence
1Optical Imaging Laboratory, Biomedical Engineering Program, Texas A&M University, College Station, Texas 77843-3120, USA.
Abstract:
An optical imaging technique that is believed to be novel was developed for noninvasive cross-sectional imaging of tissuelike turbid media. By use of a sonoluminescence signal generated internally in the media with a 1-MHz continuous-wave ultrasound, two-dimensional images were produced for objects embedded in turbid media by a raster scan of the media. Multiple objects of different shapes were resolved with this imaging technique. The images showed a high contrast and good spatial resolution. The spatial resolution was limited by the focal size of the ultrasonic focus.
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