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Updated: Jul 7, 2026

Optimization of Crystal Growth for Neutron Macromolecular Crystallography
Published on: March 13, 2021
Synthesis of nanocrystals via microreaction with temperature gradient: towards separation of nucleation and growth
Hongwei Yang1, Weiling Luan, Shan-tung Tu
1School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai, 200237, PR China.
Abstract:
By utilizing the symmetrical temperature distribution in a tube furnace chamber, a capillary microreactor was designed with the microchannel passing two well-controlled, stable temperatures in steep temperature gradients. The two-temperature microreator, first developed and implemented by this research team, provides an opportunity to separate the nucleation and growth of semiconductor nanocrystals, leading to better control of nucleation and growth kinetics. For the synthesis of CdSe nanocrystals as a model system, we demonstrated the improved size uniformity achieved by the two-temperature approach, confirming the success of the use of high temperature to burst nucleation and low temperature to promote growth.
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