Related Experiment Video
Updated: Jul 7, 2026

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
Published on: May 23, 2025
Topical anesthetic pledgett system (TAPS) for intravitreal injection preparation
1Eyecare Medical Group Portland, ME 04072, USA. darrin@brysontaylor.com
A novel topical anesthetic pledget (TAP) delivery system enhances patient comfort and staff efficiency during intravitreal injections. This hands-free method ensures effective anesthetic coverage and streamlines pre-injection preparation.
Area of Science:
- Ophthalmology
- Anesthesiology
- Surgical Preparation
Background:
- Intravitreal injections are a common ophthalmic procedure requiring effective patient preparation.
- Traditional topical anesthetic delivery methods may have limitations in efficacy and efficiency.
- Pledget drug delivery has a history of success in ophthalmology for various applications.
Purpose of the Study:
- To design and evaluate a novel topical anesthetic delivery method for intravitreal injections.
- To achieve effective anesthetic coverage and enhance patient comfort.
- To improve staff productivity and patient flow in an ophthalmology practice.
Main Methods:
- Preparation of a tubular pledget using cotton soaked in 4% Lidocaine.
- Placement of the pledget in the inferior fornix, covering the intended injection site.
- A hands-free approach allowing patients to close their eyes for 5-7 minutes.
Main Results:
- Patients reported no discomfort during pledget placement and minimal discomfort during injection.
- The method demonstrated effective anesthetic coverage.
- Staff productivity increased due to the hands-free nature and potential for simultaneous preparation.
Conclusions:
- The topical anesthetic pledget (TAP) delivery system is an effective and efficient tool for intravitreal injections.
- This system addresses the growing need for improved anesthetic delivery and workflow optimization.
- The TAP system offers a reproducible and comfortable preparation method for patients undergoing intravitreal procedures.
Related Concept Videos
Ophthalmic Drug Delivery Systems
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Parenteral Anesthetics: Overview
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

