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Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

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Related Experiment Video

Updated: Jul 7, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Allergic rhinitis in children with asthma: a questionnaire-based study.

S Hamouda¹, C Karila, T Connault

¹Université Paris Descartes, Assistance Publique des hôpitaux de Paris, Hôpital Necker Enfants Malades, Service de Pneumologie et d'Allergologie Pédiatriques, Paris, France.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology

|March 1, 2008

Summary

Allergic rhinitis (AR) is common in children with asthma, affecting 58.7%. This study found AR is not a risk factor for asthma severity in children. A modified questionnaire effectively identifies AR in this population.

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

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Last Updated: Jul 7, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Area of Science:

Pediatric Allergy and Immunology
Respiratory Medicine
Clinical Epidemiology

Background:

Allergic rhinitis (AR) and asthma frequently coexist in children, but this association is understudied.
Understanding the prevalence of AR in pediatric asthma patients is crucial for comprehensive management.

Purpose of the Study:

To determine the prevalence of allergic rhinitis (AR) in children diagnosed with asthma.
To investigate whether AR serves as a risk factor for increased asthma severity in pediatric patients.

Main Methods:

A prospective study involving 404 asthmatic children (aged 3-18 years) using a modified adult Score for Allergic Rhinitis (SFAR) questionnaire.
AR and asthma were classified using ARIA and GINA 2004 guidelines, respectively.
The adapted SFAR questionnaire demonstrated high diagnostic accuracy for AR in asthmatic children.

Main Results:

Allergic rhinitis (AR) was diagnosed in 58.7% of the asthmatic children studied.
AR was classified as intermittent in 57.8% and persistent in 42.2% of affected children.
The presence of AR did not correlate with asthma severity; similar proportions of children with mild and moderate-to-severe asthma had AR.

Conclusions:

Allergic rhinitis (AR) and asthma exhibit a high comorbidity rate (58.7%) in the pediatric population.
The adapted Score for Allergic Rhinitis (SFAR) questionnaire is a simple, reliable tool for detecting AR in children with asthma.
AR is frequently associated with childhood asthma but does not appear to be a significant risk factor for asthma severity.