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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
[Mini mental state examination. Validation of new Danish version]
Ejnar Alex Kørner1, Lise Lauritzen, Flemming Mørkeberg Nilsson
1Psykiatrisk Sygehus, Gerontopsykiatrisk Ambulatorium, Hillerød. alko@fa.dk
Ugeskrift for Laeger
|March 1, 2008
Summary
This study validated the Danish Mini Mental State Examination (MMSE) for older adults, finding it reliable for dementia screening. A score of 26 or higher is recommended, but it shouldn't solely determine dementia severity.
Area of Science:
- Gerontology
- Psychometrics
- Neurology
Background:
- The Mini Mental State Examination (MMSE) is a widely used cognitive screening tool.
- Previous versions in Denmark lacked formal validation.
- A standardized Danish MMSE with a manual was developed in 2000.
Purpose of the Study:
- To validate the new common Danish version of the Mini Mental State Examination (MMSE).
- To assess the reliability and diagnostic utility of the MMSE in a Danish psycho-geriatric population.
Main Methods:
- A longitudinal study involving 101 participants aged 65+ in four psycho-geriatric departments.
- Participants were assessed three times over 26 weeks using the Danish MMSE and global scales.
- Diagnosis was confirmed using ICD-10 criteria by a psycho-geriatrician.
Main Results:
- The Danish MMSE demonstrated high inter-rater and test-retest reliability (r=0.91).
- An optimal cut-off score of >= 26 was identified, outperforming the previously used 24.
- MMSE scores showed considerable variation within similar global severity levels.
Conclusions:
- The validated Danish MMSE is a robust and reliable tool for cognitive assessment in older adults.
- The recommended cut-off score of 26 improves diagnostic accuracy.
- The MMSE's score dispersion limits its use in precisely defining dementia severity.
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