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Discovery of heparin chemosensors through diversity oriented fluorescence library approach
Shenliang Wang1, Young-Tae Chang
1Department of Chemistry, New York University, New York, New York 10003, USA.
Chemical Communications (Cambridge, England)
|March 1, 2008
Abstract:
Two novel heparin sensors, Heparin Orange and Heparin Blue, were developed by a diversity oriented fluorescence library approach (DOFLA) from a benzimidazolium library; the discovered compounds showed remarkable properties and have the potential to be applied to monitoring heparin levels in clinical plasma samples for point-of-care detection.
