Related Experiment Video
Updated: Jul 7, 2026
Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
[Surgical management of minor salivary gland tumors]
Liang Zhou1, Xiaoling Chen, Weiting Huang
1Department of Otolaryngology-Head and Neck Surgery, Affiliated Eye Ear Nose Throat Hospital, Fudan University, Shanghai, 200031, China. zhlwc@online.sh.cn
Objective:
To study the clinical features of minor salivary gland tumors and to discuss the treatment modalities for these tumors.
Method:
Retrospective analysis of 54 cases with minor salivary gland tumor operated in our hospital from 1997 to 2004.
Result:
Among 54 cases with minor salivary gland tumors in this series, 16 patients lost of follow up. Among the remaining 38 patients, 2 patients with nasal cavity adenoid cystic carcinoma died of tumor recurrence 2 and 3 years after the surgery respectively, one patient with laryngeal myoepithelial carcinoma died of tumor recurrence 3 years after the surgery and one patient with paranasal sinus mucoepidermoid carcinoma died of recurrence 17 months after the surgery. Two patients with paranasal sinus adenoid cystic carcinoma recurred after the primary surgery and were survived without tumor after salvage surgery. The other patients survived with no tumor recurrence.
Conclusion:
While different histopathology of minor salivary gland tumors were found in this group, malignant tumors were predominant, accounting for 81.4%. The choice of treatment for minor salivary gland tumors depends upon the location and the histopathology of the tumors. The treatment policy for benign tumors is simple tumor excision, while that for malignant tumors is surgery combined with pre- or post-operative radiation therapy. Complete surgical resection of tumor masses and tumor free margin is essential for successful treatment of malignant minor salivary gland tumors.
