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Ketamine gargle for attenuating postoperative sore throat
1Faculty of Medicine, Department of Anaesthesiology, Hacettepe University, 06100 Sihhiye/Ankara, Turkey. ozgurcanbay@yahoo.com
British Journal of Anaesthesia
|March 4, 2008
Summary
Ketamine gargles effectively reduced the incidence and severity of postoperative sore throat (POST) following tracheal intubation. This intervention offers a promising solution for managing this common complication.
Area of Science:
- Anesthesiology
- Otolaryngology
Background:
- Tracheal intubation frequently causes airway mucosa trauma.
- Postoperative sore throat (POST) affects 21-65% of patients after intubation.
Purpose of the Study:
- To evaluate the efficacy of ketamine gargles in preventing POST.
- Comparison of ketamine gargles versus placebo for POST prevention.
Main Methods:
- Prospective, randomized, placebo-controlled, single-blind study.
- 46 ASA I-II patients undergoing septorhinoplasty received either saline or ketamine gargle before anesthesia.
- POST was assessed using a four-point scale at 0, 2, 4, and 24 hours post-operation.
Main Results:
- Ketamine gargle group showed lower POST incidence at 0, 2, and 24 hours.
- Significantly fewer patients in the ketamine group experienced severe POST at 4 and 24 hours (P<0.05).
Conclusions:
- Ketamine gargles significantly decrease the occurrence and intensity of POST.
- This method presents a viable strategy for mitigating POST after endotracheal intubation.
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