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[Splenic abscess in typhoid fever].

G Calleri1, F Gaiottino, M Sommo

  • 1Divisione A Malattie Infettive, Ospedale Amedeo di Savoia, Torino.

La Clinica Terapeutica
|May 31, 1991
PubMed
Summary

A splenic abscess, a rare complication of typhoid fever, occurred in a young patient despite antibiotic treatment. Surgical removal of the spleen confirmed Salmonella Typhi infection, highlighting a resurgence of this infrequent condition.

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Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Microbiology

Background:

  • Typhoid fever, caused by Salmonella Typhi, is a systemic infection.
  • Splenic abscesses were more common before the antibiotic era.
  • Modern antibiotic treatments have significantly reduced the incidence of splenic abscesses.

Observation:

  • A young patient presented with recurrent fever and left hypochondrium/shoulder pain after 21 days of treatment with thiamphenicol and ampicillin.
  • Abdominal ultrasonography indicated a splenic abscess.
  • The patient underwent splenectomy, and Salmonella Typhi was isolated from the abscess pus.

Findings:

  • The case represents a rare instance of splenic abscess secondary to typhoid fever in the modern medical era.
  • Salmonella Typhi was confirmed as the causative agent of the splenic abscess.
  • This case adds to the limited reported cases of splenic abscess since 1940.

Implications:

  • Splenic abscess should be considered in the differential diagnosis of persistent or recurrent fever after typhoid fever treatment, even with antibiotics.
  • Early diagnosis and surgical intervention (splenectomy) are crucial for managing splenic abscess.
  • This case underscores the importance of vigilance for rare complications of common infections.

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