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Blepharitis--a diagnostic and therapeutic challenge. A report on 407 consecutive cases
V Huber-Spitzy1, I Baumgartner, K Böhler-Sommeregger
12nd Department of Ophthalmology, University of Vienna, Austria.
Summary
Chronic blepharitis cases have risen, with Staphylococcus aureus decreasing but staphylococcal blepharitis persisting. Investigations reveal shifts in microorganisms causing this eye inflammation.
Area of Science:
- Ophthalmology
- Dermatology
- Microbiology
Background:
- Increasing prevalence of chronic bilateral blepharitis cases observed.
- Associated conditions include Keratoconjunctivitis sicca (KCS) in 14.5% of acne rosacea patients.
- Previous microbial spectrum differs from current findings.
Purpose of the Study:
- To investigate the changing microbiological landscape of chronic blepharitis.
- To analyze clinical presentation, microbial findings, and treatment of blepharitis.
- To compare current microbial data with historical data.
Main Methods:
- Ophthalmological and dermatological investigations of 407 patients diagnosed with chronic bilateral blepharitis between January 1985 and December 1989.
- Microbiological analysis of affected sites.
- Comparison of current microbial data with historical records.
Main Results:
- Staphylococcus aureus prevalence has significantly decreased compared to the pre-antibiotic era.
- Staphylococcal blepharitis remains a distinct entity, present in 62.8% of patients, alone or with seborrheic blepharitis.
- A shift in the spectrum of microorganisms associated with chronic blepharitis was identified.
Conclusions:
- The microbial profile of chronic blepharitis has evolved over recent years.
- Staphylococcal blepharitis, though less common, persists as a significant diagnosis.
- Understanding these shifts is crucial for effective clinical management and therapy.
