Tetraarylphosphonium-supported carbodiimide reagents: synthesis, structure optimization and applications

Maryon Ginisty1, Marie-Noelle Roy, Jean-Christophe Poupon

  • 1Département de Chimie, Université de Montréal, PO Box 6128, Station Downtown, Montréal, Canada QC H3C 3J7.

Summary

New tetraarylphosphonium (TAP)-supported carbodiimides act as efficient coupling reagents for esterification and amidation. These reagents facilitate easy separation of by-products and can be regenerated, offering a sustainable approach to organic synthesis.