In vivo confocal and multiphoton microendoscopy
Related Experiment Video
Updated: Jul 7, 2026

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging
Published on: January 11, 2011
Pilhan Kim1, Mehron Puoris'haag, Daniel Côté
1Harvard Medical School and Massachusetts General Hospital, Wellman Center for Photomedicine, 50 Blossom St., BAR 818, Boston, Massachusetts 02114, USA.
Abstract:
The ability to conduct high-resolution fluorescence imaging in internal organs of small animal models in situ and over time can make a significant impact in biomedical research. Toward this goal, we developed a real-time confocal and multiphoton endoscopic imaging system. Using 1-mm-diameter endoscopes based on gradient index lenses, we demonstrate video-rate multicolor multimodal imaging with cellular resolution in live mice.
Related Concept Videos
Confocal Fluorescence Microscopy
Three-Dimensional Microscopy in Microbiology
Super-resolution Fluorescence Microscopy

