Related Experiment Video
Updated: Jul 7, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
Published on: November 15, 2013
Look who's talking: nuclear receptors in the liver and gastrointestinal tract
Michael Downes1, Christopher Liddle
1Howard Hughes Medical Institute, Gene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Abstract:
The Nuclear Receptors in Liver and Digestive Diseases research workshop was held in Rockville, Maryland, on November 7 and 8, 2007, under the auspices of the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. Over 130 researchers from around the world gathered to assess the pathophysiology of nuclear receptors in the liver and gastrointestinal tract and to explore their potential use as therapeutic targets. This review covers some of the highlights of the meeting, including important areas of future investigation.
Related Concept Videos
Transducer Mechanism: Nuclear Receptors
About 48 different soluble family members of nuclear receptors are identified that can be divided into two main classes:
Signal Transduction: Overview
Typically, signal transduction involves three...
Intracellular Hormone Receptors
Regulation of Nuclear Protein Sorting
Nuclear Export
NES are of three types- the canonical 10-residue long leucine-rich signal and other...
Internal Receptors
