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Updated: Jul 7, 2026

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
Published on: September 12, 2020
Dystonic frowning without blepharospasm
Nobuyuki Hirota1, Mari Hirota, Takahiro Mezaki
1Department of Neurology, Otsu Municipal Hospital, Otsu City, Shiga 520-0804, Japan.
Abstract:
We report on two cases who presented with involuntary facial grimacing and frowning. Blepharospasm has never been documented in one, and the other case showed difficulty in lid opening only in the early phase of the disease. Botulinum toxin was effective for both. This is a hitherto unreported presentation of upper facial dystonia without interference of eyelid motor control.
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