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History of infections associated with combat-related injuries

Clinton K Murray1, Mary K Hinkle, Heather C Yun

  • 1San Antonio Military Medical Center, Fort Sam Houston, Texas, USA. Clinton.Murray@amedd.army.mil

The Journal of Trauma
|March 20, 2008
PubMed

Insights

War wound infections, despite antibiotics, remain a major cause of death and illness. This review examines the history of wound microbiology and combat casualty care from World War I through the 20th century.

Area of Science:

  • Military medicine
  • Infectious diseases
  • Wound healing

Background:

  • War wounds consistently present with devitalized tissue, foreign bodies, clots, fluid, and microbial contamination.
  • Despite advances like antibiotics, war wound infections remain a significant cause of morbidity and mortality.
  • Evolving microbial resistance patterns necessitate continuous adaptation in therapeutic strategies.

Observation:

  • This review details the historical trajectory of war wound infections.
  • Focuses on wound microbiology and the evolution of combat casualty management.
  • Covers US conflicts from World War I to the end of the 20th century.

Findings:

  • Historically, war wounds share common pathological features regardless of conflict era.
  • Microbial contamination and subsequent infection have been persistent challenges.
  • Combat casualty care has evolved significantly in response to these challenges.

Implications:

  • Understanding historical trends in war wound infections informs current and future medical readiness.
  • Highlights the critical interplay between wound management and antimicrobial stewardship.
  • Provides context for the ongoing battle against infectious complications in combat casualties.

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