A case of fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion
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Savas Ozturk1, Ekmel Burak Ozsenel, Rumeyza Kazancioglu
1Department of Nephrology, Haseki Training and Research Hospital, Millet Cad, Haseki, Istanbul 34330, Turkey. savasozturkdr@yahoo.com
Background:
A 58-year-old schizophrenic male who had been drinking at least 4-5 l of pure water every day for 30 years was admitted to a hospital with complaints of nausea, fatigue, and irregular, fluctuating fevers (up to 39 degrees C). He had previously been prescribed fluoxetine at a dose of 20 mg/day and had been using the drug for 28 days.
Investigations:
Review of medical history, physical examination, blood analysis, urine analysis, chest radiography and abdominal ultrasound.
Diagnosis:
Psychogenic polydipsia and fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion.
Management:
Fluid restriction and discontinuation of fluoxetine.
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