Pregnancy following gastric bypass surgery for morbid obesity: maternal and neonatal outcomes

The purpose of this study was to compare obstetric and neonatal outcomes after Roux-en-Y gastric bypass (RYGB) to those in women without such surgery.

Women with RYGB (cases) were matched for maternal age and prior cesarean to the next two consecutive women delivering without prior bariatric surgery (controls). Pregnancy and newborn outcomes were compared by univariate analysis. Outcomes approaching or reaching statistical significance were evaluated by conditional logistic regression controlling for maternal body mass index (BMI).

Despite gastric bypass, the 38 cases were heavier (BMI 33.4+/-7.3 vs. 28.1+/-6.7 kg/m2, p<0.001) and more often obese (BMI> or =30 kg/m2, 26/38 (68.4%) vs. 20/76 (26.3%), p<0.001) than controls. Variables evaluated by logistic regression adjusted for BMI did not differ in cases versus controls, including hypertension (odds ratio [OR] 2.62, 95% confidence interval [CI] 0.66-10.50), preterm premature rupture of membranes (OR 0.24, 95% CI 0.02-3.38), oligohydramnios (OR 2.39, 95% CI 0.66-8.61), and delivery > or =41 weeks (OR 0.57, 95% CI 0.11-2.97).

Obstetric and neonatal outcomes after RYGB are similar to those of our general obstetric population.