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Updated: Jul 6, 2026

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

Published on: January 20, 2022

Comparative glycomics of connective tissue glycosaminoglycans

Alicia M Hitchcock1, Karen E Yates, Catherine E Costello

  • 1Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.

Proteomics
|March 5, 2008
PubMed

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Matrix Proteoglycans and Glycoproteins

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In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.Composition of the Extracellular MatrixThe extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse molecules.