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Updated: Jul 6, 2026

Single Step Isolation of Extracellular Vesicles from Large-Volume Samples with a Bifurcated A4F Microfluidic Device
Published on: February 2, 2024
Optical particle-sizing method that provides optical isolation of the sampling volume
V M Kustov1, D A Markov, D J Mehrl
1Department of Electrical Engineering, Texas Tech University, MS-43102, Lubbock, Texas 79409, USA. zlm01@ttacs.ttu.edu
Abstract:
We have constructed and tested a novel particle sizer that employs particle counting (the time-domain approach) rather than the ensemble-diffraction approach that currently dominates the market in atmospheric-dust particle sizers. The method does not depend on mechanical devices to restrict particles within the sampling volume but instead allows for optical isolation of the sampling volume. This technique is useful for atmospheric-dust measurements for which nonobtrusive measurement is often desirable.

