Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hepatitis B: evolving epidemiology and implications for control.

H S Margolis¹, M J Alter, S C Hadler

¹Hepatitis Branch Centers for Disease Control, Atlanta, Georgia 30333.

Seminars in Liver Disease

|May 1, 1991

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparing ultrastable lasers at 7 × 10<sup>-17</sup> fractional frequency instability through a 2220 km optical fibre network.

Nature communications·2022

Same author

Test of Special Relativity Using a Fiber Network of Optical Clocks.

Physical review letters·2017

Same author

Frequency Comparison of [Formula: see text] Ion Optical Clocks at PTB and NPL via GPS PPP.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2016

Same author

Transportable cavity-stabilized laser system for optical carrier frequency transmission experiments.

Applied optics·2015

Same author

Frequency ratio of two optical clock transitions in 171Yb+ and constraints on the time variation of fundamental constants.

Physical review letters·2014

Same author

The inception, achievements, and implications of the China GAVI Alliance Project on Hepatitis B Immunization.

Vaccine·2013

Same journal

Endothelial Cell Therapy for the Acute and Chronic Liver Disease.

Seminars in liver disease·2026

Same journal

Neutrophils in Liver Diseases: Functions and Challenging Therapies.

Seminars in liver disease·2026

Same journal

Expert Practical Recommendations for Hepatocellular Carcinoma.

Seminars in liver disease·2026

Same journal

Optimizing Liver Cancer Care Through BCLC Principles.

Seminars in liver disease·2026

Same journal

Patient-Derived Models of Liver Cancer to Inform Clinical Treatment Paradigms: Recent Updates.

Seminars in liver disease·2026

Same journal

Practical Guide to Best Practices in Alcohol-Associated Liver Disease.

Seminars in liver disease·2026

See all related articles

Hepatitis B vaccination can control and eliminate HBV transmission. Current strategies in low-prevalence areas like the US are ineffective, necessitating a comprehensive approach for all age groups.

Area of Science:

Hepatology
Vaccinology
Public Health

Background:

Hepatitis B virus (HBV) infection is a global health concern linked to chronic liver disease and hepatocellular carcinoma.
Effective hepatitis B vaccination strategies are crucial for controlling and potentially eliminating HBV transmission.
Current vaccination approaches in low-prevalence regions have limitations in addressing the diverse epidemiology of HBV infection.

Purpose of the Study:

To evaluate the effectiveness of current hepatitis B vaccination strategies in low-prevalence areas.
To highlight the challenges in vaccine delivery to adult populations at risk.
To advocate for a comprehensive approach to HBV transmission elimination.

Main Methods:

Review of existing hepatitis B vaccination strategies and their epidemiological impact.

Related Experiment Videos

Analysis of HBV infection patterns in different risk groups and age demographics.

Assessment of vaccine delivery challenges in the United States and similar regions.

Main Results:

Childhood vaccination is effective in high-prevalence areas but insufficient in low-prevalence regions.
Current US strategies primarily reach occupational exposure groups, missing the majority of adult infections.
HBV infections in low-prevalence areas are predominantly acquired by adults, often before risk awareness.

Conclusions:

Current hepatitis B vaccination strategies in the US are not fully effective in controlling HBV transmission.
A comprehensive approach is needed, addressing childhood, adolescent, and adult HBV infections.
Reevaluation of vaccine delivery and targeting is essential for HBV elimination.