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Larval RNA Interference in Silkworm Bombyx mori through Chitosan/dsRNA Nanoparticle Delivery
Published on: October 4, 2024
[Alkaloid constituents from silkworm dropping of Bombyx mori]
Guang-xiong Zhou1, Jie-wu Ruan, Mei-yan Huang
1Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Objective:
To extract and isolate chemical constituents from the total alkaloids of silkworm dropping (Can Sha) of Bombyx mori L.
Methods:
Chemical constituents were isolated by column chromatography with macroporous adsorbent resin, ion-exchange resin and sephadex LH 20. The structures of the isolated compounds were determined by spectral means.
Results:
Three compounds were isolated and identified as 1-deoxynojirimycin (1) , fagomine (2) , and 3-epifagomine (3) on the basis of their 1H-NMR, 13C-NMR spectra and ESIMS data.
Conclusion:
Compounds 1-3 are isolated and identified from Can Sha for the first time.
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