[Supercritical coupling traditional way to extract flavones in Saussurea involucrate]

The Saussures involucrate was pretreated with supercritical CO2, then the residue was extracted with ethanol. Using a method of orthogonal experiment, the influence of temperature, time, liquid/solid ratios, the concentration of ethanol to the total flavones content were investigated. Compared with traditional extraction method, about more than 10.07%-128.4% flavones were obtained. In conclusion, the supercritical coupling traditional way could enhance the extraction efficiency, lower the extraction temperature, shorten the lixiviating time, reduce the losing of effective component, and pre-extract the plants (obtain about 2.45% oil segment). The study developed a new application of supercritical technology in the extraction of natural resources.