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Published on: June 2, 2022
Coffee consumption and coronary calcification: the Rotterdam Coronary Calcification Study
Geertruida J van Woudenbergh1, Rozemarijn Vliegenthart, Frank J A van Rooij
1Division of Human Nutrition, Wageningen University, Wageningen, P.O. Box 8129, 6700 EV Wageningen, The Netherlands.
Arteriosclerosis, Thrombosis, and Vascular Biology
|March 8, 2008
Summary
Coffee consumption may reduce coronary calcification, especially in women. This study found a beneficial effect of moderate to high coffee intake on preventing hardened arteries, though more research is needed.
Area of Science:
- Cardiovascular Health
- Nutritional Epidemiology
- Preventive Cardiology
Background:
- The impact of coffee on cardiovascular health remains uncertain.
- Existing research has not definitively established a link between coffee intake and coronary calcification.
Purpose of the Study:
- To investigate the association between coffee consumption and coronary calcification.
- To determine if coffee intake influences the risk of developing coronary artery disease.
Main Methods:
- A population-based cohort study involving 1570 older adults without pre-existing coronary heart disease.
- Coffee intake was quantified using a semiquantitative food frequency questionnaire.
- Coronary calcification was assessed using electron beam computed tomography, with severe calcification defined as an Agatson calcium score >400.
Main Results:
- In women, moderate (>3–4 cups) and high (>4 cups) daily coffee intake were associated with significantly reduced odds of coronary calcification compared to consuming 3 cups or less.
- These findings in women persisted after adjusting for various dietary factors and were not influenced by smoking status.
- A nonsignificant inverse relationship was observed in male smokers, while nonsmoking men showed a direct association between coffee intake and coronary calcification.
Conclusions:
- Coffee consumption appears to have a protective effect against coronary calcification, particularly in women.
- Further research is warranted to confirm these results and explore potential gender and smoking-related effect modifications.
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