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NLX-112, a highly selective 5-HT1A receptor biased agonist, does not exhibit misuse potential in male rats or macaques.

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NLX-101, a highly selective 5-HT1A receptor biased agonist, mediates antidepressant-like activity in rats via prefrontal cortex 5-HT1A receptors.

Behavioural brain research·2020

The selective 5-HT1A receptor agonist, NLX-112, exerts anti-dyskinetic effects in MPTP-treated macaques.

Parkinsonism & related disorders·2020

Bell-shaped agonist activation of 5-HT1A receptor-coupled Gαi3 G-proteins: Receptor density-dependent switch in receptor signaling.

Cellular signalling·2019

Insights into the regulation of the HOTAIR proximal promoter.

Biochemical Society transactions·2026

Distinct functions of mammalian RAD51 paralogs in genome maintenance.

Biochemical Society transactions·2026

Glycosylation of the retina.

Biochemical Society transactions·2026

Tools to investigate class B1 GPCR conformational landscapes with cryo-EM and beyond.

Biochemical Society transactions·2026

The molecular mechanisms of crista formation: how mitochondria give themselves breathing room.

Biochemical Society transactions·2026

Propionic acidemia as a framework for understanding the impact of disturbed propionyl-CoA on histone modifications.

Biochemical Society transactions·2026

Evaluation of basal cortisol and the adrenocorticotropic hormone stimulation test in 982 dogs undergoing investigation for hypoadrenocorticism.

Journal of veterinary internal medicine·2026

Does kidney function in experimental porcine sepsis fulfill the RIFLE criteria for acute kidney injury? A systematic review.

Frontiers in physiology·2026

Prospective single-arm study of gastric surgery in experimental animals assisted by Kangduo surgical robot.

International journal of surgery (London, England)·2026

Automated Behavioral Tracking and Analysis of Xenopus Tadpoles.

Methods in molecular biology (Clifton, N.J.)·2026

Standardization and quality control in PET imaging: Advances, challenges, and clinical implications.

Radiography (London, England : 1995)·2026

Animal organoids as models for integrated One Health research.

One health (Amsterdam, Netherlands)·2026

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Contrasting Behavioural and Biochemical Characteristics of Normal and Spontaneously α-Synuclein-Deficient Mice Treated With MPTP.

Acute and Repeated Administration of NLX-101, a Selective Serotonin-1A Receptor Biased Agonist, Reduces Audiogenic Seizures in Developing Fmr1 Knockout Mice.

NLX-112, a highly selective 5-HT1A receptor biased agonist, does not exhibit misuse potential in male rats or macaques.

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