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Updated: Jul 6, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Endometrial osseous metaplasia: an evolving cause of secondary infertility
Lutfu Sabri Onderoglu1, Hakan Yarali, Murat Gultekin
1Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Sihhiye, Ankara, Turkey.
Objective:
To present an endometrial osseous metaplasia case and reemphasize that the condition is a cause of secondary infertility.
Design:
Case report.
Setting:
Department of Obstetrics and Gynecology in a university hospital in Turkey.
Patient(S):
A 33-year-old multiparous woman was admitted to our institution with secondary infertility that had lasted for 2 years. She had experienced one first-trimester and one second-trimester abortion, 3 years and 2 years ago, respectively. On transvaginal sonography, a linear curvy echogenity was observed.
Intervention(S):
Hysteroscopic examination revealed multiple bony spicules, extending perpendicularly from the posterior uterine wall in to the uterine cavity and occupying almost two thirds of the cavity. Thereafter, a resectoscopic excision of the bony spicules was performed.
Main Outcome Measure(S):
A normal endometrium and uterine cavity.
Result(S):
Two weeks after the operation, ultrasonographic evaluation was in the normal range, and the patient currently is trying to conceive spontaneously.
Conclusion(S):
Although the role of office hysteroscopy in the evaluation of infertile couple is still under debate, clinicians should keep this rare disorder in mind, especially in patients with a history of late abortion, and should evaluate such cases by hysteroscopy when sonographic features are encountered.
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