Mesothelial/monocytic incidental cardiac excrescence
Mohammad Ali Boroumand1, Maryam Sotoudeh Anvari, Namvar Movahedi
1Department of Clinical Research, Tehran Heart Center, Medical Sciences/University of Tehran, Tehran, Iran.
Abstract:
Mesothelial/monocytic incidental cardiac excrescence (MICE) is a very uncommon lesion. Diagnosis is incidental and may simulate thrombotic lesions. One of the hypotheses with regard to the etiology of this lesion is a previous cardiac procedure especially mitral valve repair or commissurotomy. Herein, we describe a MICE incidentally found in a patient who underwent mitral valve replacement, as a thrombotic lesion on the left atrial auricle. Histopathologic examination suggested MICE lesions and immunohistochemical stains confirmed it.
Insights
Mesothelial/monocytic incidental cardiac excrescence (MICE) is a rare cardiac lesion. This case report describes MICE found after mitral valve replacement, initially mistaken for a thrombus.
Area of Science:
- Cardiovascular Pathology
- Surgical Pathology
Background:
- Mesothelial/monocytic incidental cardiac excrescence (MICE) is an exceptionally rare cardiac lesion.
- MICE diagnosis is often incidental and can be misdiagnosed as thrombotic lesions.
- Previous cardiac procedures, particularly mitral valve interventions, are hypothesized as potential causes.
Observation:
- This report details a MICE case discovered incidentally in a patient post-mitral valve replacement.
- The lesion was initially identified as a thrombotic lesion on the left atrial auricle.
- Histopathological examination and immunohistochemical staining were crucial for definitive diagnosis.
Findings:
- Histopathology suggested MICE, which was confirmed by immunohistochemical analysis.
- The findings highlight the importance of differential diagnosis in cardiac lesions post-surgery.
- This case expands the understanding of MICE presentation and etiology.
Implications:
- Accurate identification of MICE is crucial to avoid misdiagnosis and unnecessary interventions.
- The case supports the hypothesis linking MICE to prior cardiac surgical procedures.
- Further research into MICE etiology and clinical significance is warranted.
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