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[Clinico-pathological study of contralateral lymph node metastasis in pyriform sinus carcinoma]
Objective:
To study the related factors of contralateral lymph node metastasis in pyriform sinus carcinoma.
Method:
Fifty-three patients with pyriform sinus carcinoma underwent simultaneous neck dissection from Oct. 1993 to Oct. 1999 were collected. Transparent lymph node selection and continuous slicing method were used on the postoperative specimens to observe the status of cervical lymph node metastasis. The relationship between contralateral lymph node metastasis and clinico-pathological factors, ipsilateral neck metastatic status were analyzed by the follow-up data.
Result:
Cervical lymph node metastatic rate was 79.2% in 53 patients with pyriform sinus carcinoma. Contralateral cervical lymph node metastatic rate was 35.8%. Contralateral neck metastasis was closely related with clinical N stage, cell differentiation, fused metastasis and extracapsular spread of ipsilateral neck.
Conclusion:
Contralateral neck dissection should be undertaken in patients with N2,3, moderate and low cell differentiation, or fused fused metastasis and extracapsular spread of ipsilateral neck.
