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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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Related Experiment Video

Updated: Jul 6, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
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Idiopathic temporal bone encephalocele.

V Papanikolaou1, A Bibas, E Ferekidis

  • 11st Department of Otolaryngology, Hippokration Hospital, University of Athens Medical School, Athens, Greece.

Skull Base : Official Journal of North American Skull Base Society ... [Et Al.]
|March 12, 2008
PubMed
Summary

This study details a rare case of adult-onset temporal bone meningoencephalocele, a brain tissue herniation. Surgical management involved amputation and layered closure, showing successful outcomes without relapse after twelve months.

Keywords:
Temporal bonebrain herniationmeningoencephalocele

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Area of Science:

  • Neurosurgery
  • Otolaryngology
  • Skull Base Surgery

Background:

  • Meningoencephaloceles involve brain tissue herniation through skull base defects, which can be acquired or spontaneous.
  • Spontaneous temporal bone meningoencephaloceles are rare, typically congenital, and present in childhood, with adult idiopathic cases being infrequent.
  • This case focuses on an adult-onset spontaneous temporal bone meningoencephalocele.

Observation:

  • A rare case of adult-onset temporal bone meningoencephalocele is presented.
  • The patient underwent an exploratory mastoidectomy.
  • The herniated meningoencephalocele was amputated, and the defect was closed using temporalis fascia and a pedicled muscular flap.

Findings:

  • The surgical closure technique, without bony defect reconstruction, proved adequate.
  • A twelve-month follow-up demonstrated no recurrence of the meningoencephalocele.
  • No postoperative complications were observed during the follow-up period.

Implications:

  • This case highlights a successful surgical approach for adult-onset temporal bone meningoencephaloceles.
  • It suggests that layered closure may be sufficient for managing such defects, potentially avoiding complex bony reconstruction.
  • The findings contribute to understanding the management of rare skull base pathologies.