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Updated: Jul 6, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Allergic contact dermatitis with a fertilizer containing hydrogen cyanamide (Dormex)
Caterina Foti1, Domenico Bonamonte, Anna Conserva
1Department of Internal Medicine, Immunology and Infectious Diseases, Unit of Dermatology, University of Bari, Bari, Italy. c.foti@dermatologia.uniba.it
Abstract:
Cyanamide is a chemical substance used in the treatment of chronic alcoholism as well in agriculture as a fertilizer. We report the case of a 28-year-old healthy non-atopic man that developed a severe skin eruption after the accidental penetration of a small amount of Dormex (a plant growth regulator containing cyanamide) through the patient's gloves. Patch tests revealed positive reactions to Dormex 1% pet. and cyanamide at a dilution of 0.1% pet. and 1% pet. We discuss the causes of sensitization in a patients that regularly used protective measures during anti-parasites treatments.
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